Pathophysiology of heatstroke in dogs – revisited

Heatstroke: thermoregulation, pathophysiology, and predisposing factors.

Heatstroke is a common veterinary emergency that, depending on the severity of injury, can progress to a life-threatening condition. Heatstroke can be classic (nonexertional) or exertional. Classic heatstroke develops when the body is exposed to high external temperatures, whereas exertional heatstroke is caused by strenuous exercise. Thermoregulation is the intrinsic ability of the body to mai...

Heatstroke pathophysiology: the energy depletion model.

This symposium focuses on exertional heatstroke, with emphasis on predisposing factors, clinical observations, diagnosis, treatment and recovery. The serious challenge to cardiovascular stability presented by exercise hyperthermia and some aspects of regulatory failure was reviewed in the introduction. The intent of this review, to understand how heat stress is translated into heat strain at th...

Pathological findings in dogs with fatal heatstroke.

Eleven dogs with fatal heatstroke were examined grossly and histopathologically post mortem. All showed multi-organ haemorrhagic diathesis with coagulative necrosis. Hypaeremia and diffuse oedema were observed in the skin (eight dogs), lungs (11), brain (11) and bone marrow (one). Congestion of the splenic pulp (10 dogs) and hepatic sinusoids (nine) was also noted. Necrosis was observed in the ...

Hypercoagulability in dogs: pathophysiology.

The risk of hypercoagulability is increased when the hemostatic balance between procoagulant and anticoagulant mechanisms is shifted in favor of coagulation. Hypercoagulability is an increasingly recognized contributor to the deleterious manifestations of veterinary disease. The basis for thrombus formation in many acquired diseases is being investigated and more clearly defined. A thorough und...

Application of a model of exertional heatstroke pathophysiology to cocaine intoxication.